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agents

ADCs – From Lab to Clinical Development

Antibody-drug conjugates (ADCs) are a family of targeted therapeutic agents for the treatment of cancer. Compared to traditional small-molecule approaches, ADCs offer enhanced targeting of …

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cancer

Regeneron buys control of cancer drug Libtayo from Sanofi

Dive Brief: Regeneron will pay partner Sanofi $900 million to gain global rights to the companies’ cancer immunotherapy Libtayo, announcing Thursday a deal executives said would …

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blood

Merck study results signal blood cancer potential for new type of immunotherapy

For years, Merck & Co. has had an upper hand over its chief cancer drug competitor Bristol Myers Squibb. In March, however, Bristol Myers beat …

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Amgen

Mirati matches Amgen with updated data for KRAS-blocking cancer drug

Mirati Therapeutics hopes to later this year win U.S. approval of only the second drug able to target tumors spurred by mutations in an elusive …

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cancer

Roche cancer immunotherapy fails another trial, casting doubt on emerging drug class

Dive Brief: A drug combination including Roche’s experimental immunotherapy tiragolumab failed one of two main goals in a Phase 3 trial in a common form …

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cancer

Taiho, chasing larger rivals, buys back rights to Cullinan cancer drug

Dive Brief: Taiho Pharmaceutical is buying back rights to an experimental cancer drug aimed at a genetic driver of lung tumors after licensing it to …

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AstraZeneca

AstraZeneca and Daiichi set to broaden use of breast cancer drug, challenging Roche

Dive Brief: The Food and Drug Administration approved the antibody treatment Enhertu for earlier use in breast cancer patients, the latest milestone for a drug …

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cancer

Novartis suspends production of two radiopharmaceutical drugs over quality concerns

Dive Brief: Novartis has suspended production of two cancer drugs at plants in Italy and New Jersey due to “potential quality issues” it identified in …

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cancer

Cancer Research UK reveals innovation engine underpinned by £400m portfolio of cutting-edge discovery science

Cancer Research UK, the world’s largest independent funder of cancer research, today (Tuesday 26th), unveiled Cancer Research Horizons, its new and ambitious approach to driving …

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biotechnology

A promising cancer drug leads Regeneron to reconsider its aversion to M&A

Dive Brief: Regeneron has agreed to purchase a young biotechnology company for access to a drug that the buyer believes will be a valuable component …

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cancer

Seagen to expand, add jobs with new cancer drug factory

Dive Brief: Seagen, the largest biotechnology company in the Seattle area, has unveiled plans for a manufacturing facility to help provide “greater control and flexibility” …

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blood

FDA panel supports agency push to raise approval bar for certain cancer drugs

The Food and Drug Administration appears ready to raise its approval standards for a well-known class of cancer drugs due to concerns they aren’t helping …

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cancer

GSK acquires Sierra Oncology, betting $2B on a bone cancer drug with a long history

GlaxoSmithKline has agreed to acquire Sierra Oncology for $1.9 billion in a bet that an experimental drug the small biotech developed is on the cusp …

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cancer

AACR 2022: NK cell promise, more TIGIT questions and extending CAR-T’s reach

Each year, the American Association for Cancer Research’s conference spotlights promising early research into new approaches for attacking tumors. This year’s meeting, held in person …

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cancer

FDA clears Gilead to restart some studies of top cancer drug

Dive Brief: The Food and Drug Administration has cleared Gilead to restart some trials testing an experimental cancer drug the company acquired in a roughly …

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breast

Novartis breast cancer drug approved for ultra-rare condition

Dive Brief: The Food and Drug Administration has approved the first drug to treat an ultra-rare cluster of conditions caused by mutations in a specific …

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cancer

Roche’s top immunotherapy prospect fails study in tough-to-treat lung cancer

Dive Brief: A drug combination including the Roche immunotherapy tiragolumab failed a Phase 3 trial in a tough-to-treat form of lung cancer, a setback for …

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cancer

How Merck’s ‘puzzling’ results could impact immunotherapy’s role in early lung cancer

An immunotherapy from Merck & Co. is the latest drug of its kind to slow the return of lung cancer in clinical testing, though mixed …

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cancer

FDA sets back Karyopharm’s bid to broaden use of cancer drug

Dive Brief: Karyopharm Therapeutics will have to perform a new clinical trial to widen the use of its cancer drug selinexor after U.S. regulators said …

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AstraZeneca

AstraZeneca, Daiichi press rivals with new results for breast cancer drug

Dive Brief: AstraZeneca and Daiichi Sankyo’s antibody drug Enhertu could become standard treatment for a large group of breast cancer patients following Phase 3 study …

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